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Nucleic Acids and Proteins: The Interactions of Nucleotide Bases
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<strong>Nucleic Acids and Proteins:</strong> The Interactions of
Nucleotide Bases
</p>
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<p class="mainidea">
What makes the nucleotides fit together well in a double helix?
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<p class="subhead">
The complementarity of nucleotides
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In the cell, DNA forms a double helix made of two chains, or <b>strands</b>,
of nucleotides. <b>In certain combinations, the bases of the nucleotides
fit together well</b> which allows them to form <b>hydrogen bonds</b> to
each other.
</p>
<!-- <a href="script:page:0:message complementary.html">complementary</a> -->
<p>
<strong>What to do:</strong> Make a new DNA strand in the model below to
find out which nucleotide bases fit together well enough to form
multiple hydrogen bonds with each other.
</p>
<ol>
<li>
<b>You can drag the four bases, A, C, G, and T, on the top row</b>
near each of the bases on the bottom row, one at a time. You will see
dotted lines appear between some of the atoms. The dotted lines
represent <a href="script: page:0:message hbonds-definition.html">hydrogen
bonds</a>.
</li>
<li>
<b>Place the bases near the green circles to form a new DNA strand
with the largest number of hydrogen bonds</b> between the two strands
of DNA.
</li>
</ol>
<font size="2">Note that to simplify the structures, not all hydrogen
atoms are shown on the nucleotide bases.</font>
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<body class="question">
<p class="question">
What is the largest <b>total </b>number of hydrogen bonds you can form
in the model?
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Insert the snapshot that shows how you arranged the nucleotide bases for
the greatest number of hydrogen bonds.
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<p class="question">
The cell is capable of making new strands of DNA by pairing nucleotides
opposite each other, as you did in the model above. Using what you
learned about fitting the bases as opposite pairs, what would be the
nucleotides in a strand opposite ATTCGATCAT?
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