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From DNA to Proteins: Stop codons
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<font size="5" color="#FFFFFF" face="Verdana, Arial, Helvetica, sans-serif"><strong>From
DNA to Proteins:</strong> Stop codons</font>
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<font size="4" face="Verdana, Arial, Helvetica, sans-serif"><strong>Stop
codons </strong>don't code for an amino acid, as do other codons.
Instead, they signal the end of the protein. Inserting a stop codon
into the sequence will cause translation to stop there.</font>
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<font><a link_width="500" link_left="500" link_menubar="false" link_toolbar="false" link_height="450" href="geneticCodeTableStatic.cml" target="_blank" link_statusbar="false" link_top="100">Genetic
Code Table</a></font>
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<b>Challenge: make a stop codon</b><font face="sans"> </font>
<ol>
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Synthesize the unmutated protein and take a snapshot for later
reference.
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<li>
Use the <font><a link_width="500" link_left="500" link_menubar="false" link_toolbar="false" link_height="450" href="geneticCodeTableStatic.cml" target="_blank" link_statusbar="false" link_top="100">genetic
code table</a></font> to find the stop codons.
</li>
<li>
Choose a triplet somewhere in the middle of the DNA strand to change
into a stop codon.
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<li>
Synthesize your new mutated protein and take a snapshot.
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<b>Drag a snapshot image that shows the mutated protein.</b>
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<body marginwidth="5" bgcolor="rgb(230, 230, 230)" marginheight="5">
<font size="4" face="Arial, Helvetica, sans-serif"><strong>Compare the
effects of a mutation that causes an amino acid change with a mutation
that causes a stop codon. Which do you think would affect the protein
more? Why?</strong></font>
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